Building
Digital India

Publications

  1. Chanchal, Banerjee, P. and Jain, D (2017) ATP-Induced Structural Remodeling in the Antiactivator FleN Enables Formation of the Functional Dimeric Form. Structure. In Press
  2. Singhal R, Chawla S, Rathore D K, Bhasym A, Annarapu G K, Sharma V, Seth T, Guchhait P (2016) Development of pro-inflammatory phenotype in monocytes after engulfing Hb-activated platelets in hemolytic disorders.. (In Press)
  3. Annarapu GK, Singhal R, Gupta A, Chawla S, Batra H, Seth T, Guchhait P (2016) HbS Binding to GP1ba Activates Platelets in Sickle Cell Disease.. Plos One 11:e0167899
  4. Mahale S, Kumar M, Sharma A, Babu A, Ranjan S, Sachidanandan C, Mylavarapu SV (2016) The Light Intermediate Chain 2 Subpopulation of Dynein Regulates Mitotic Spindle Orientation.. Sci Rep 6:22
  5. Mahale S P, Sharma A, Mylavarapu SV (2016) Dynein Light Intermediate Chain 2 Facilitates the Metaphase to Anaphase Transition by Inactivating the Spindle Assembly Checkpoint. PLoS One 11:e0159646
  6. Chandran D, Wildermuth MC (2016) Modulation of Host Endocycle During Plant-Biotroph Interactions. Enzymes 40:65
  7. Krishnan V, Kant A, Chaurasia, P (2016) Pili in Probiotic Bacteria in "Prebiotics and Probiotics in Human Nutrition and Health", ISBN 978-953-51-4715-2, InTech:115
  8. Chaurasia P, Pratap S, von Ossowski I, Palva A, Krishnan V, (2016) New insights about pilus formation in gut-adapted Lactobacillus rhamnosus GG from the crystal structure of the SpaA backbone-pilin subunit. Sci Rep. 6:28664
  9. Annarapu GK, Singhal R, Peng Y, Guchhait P. (2016) Inhibition of Hb binding to GP1bα abrogates Hb-mediated thrombus formation on immobilized VWF and collagen under physiological shear stress. Plos One. 11:e0154276
  10. Eswaran SV, Kaurb D, Khamarue K, Prabhakarc S, Sonyc T , Raghunathand P, Gangulye B, (2016) Tuning the strain effect to induce selectivity through intramolecular nitrene insertion into an adjacent methoxy Csingle bondH bond leading to form a new benzoxazole: experimental and computational studies.Tetrahedron Letters. 57:1899
  11. Jain A, Kumar A, Salunke DM (2016) Crystal structure of the vicilin from Solanum melongena reveals existence of different anionic ligands in structurally similar pockets.Sci Rep. 6:23600
  12. Kumar A, Gupta C, Nair DT, Salunke DM. (2016) MP-4 contributes to snake venom neutralization by Mucuna pruriens seeds through an indirect antibody-mediated mechanism. J Biol Chem. 138:4522
  13. Rana S, Elci SG, Mout R, Singla AK, Yazdani M, Bender M, Bajaj A, Saha K, Bunz UHF, Jirik FR, and Rotello VM, (2016) Ratiometric Array of Conjugated Polymers-Fluorescent Protein Provides a Robust Mammalian Cell Sensor. J. Am. Chem. Soc.138:4522
  14. Kant A, von Ossowski I, Palva A, Krishnan V (2016)  Crystallization and X-ray Crystallographic Analysis of the Adhesive SpaC Pilin Subunit in the SpaCBA Pilus of Gut-adapted Lactobacillus rhamnosus GG. Protein & Peptide Letters23:365
  15. Harshita, Chanchal and Jain D (2016)  Cloning, expression, purification, crystallization and initial crystallographic analysis of FleN from Pseudomonas aeruginosa. Acta Cryst. F72, 135
  16. Gupta S, Singh M, Reddy AM, Yavvari PS, Srivastava A, and Bajaj A. (2016) Interactions governing the entrapment of anticancer drugs by low molecular weight hydrogelator for drug delivery applications. RSC Adv. 6:19751
  17. Chaurasia P, von Ossowski I, Palva A, Krishnan V. (2015) X-ray diffraction analysis of two crystals forms of backbone pilin SpaA fragment from Lactobacillus rhamnosus GG. Journal of proteins and proteomics 6:30
  18. Bhattacharya S, Hanpude P, Maiti TK. (2015)  Cancer associated missense mutations in BAP1 catalytic domain induce amyloidogenic aggregation: A new insight in enzymatic inactivation. Sci Rep 5:18462
  19. Kottur J. & Nair DT (2016) Reactive oxygen species play an important role in bactericidal activity of quinolone antibiotics. Angewandte Chemie 55: 2397
  20. Ghodke PP, Gore KR, Harikrishna S, Samanta B, Kottur J, Nair DT, Pradeepkumar PI.(2015)  The N2-Furfuryl-Deoxyguanosine (fdG) Adduct Does Not Alter the Structure of B-DNA. J Org Chem. 81:502
  21. Jain D, Naveen Narayanan, Deepak T Nair (2015) Plasticity in repressor-DNA interactions neutralizes loss of symmetry in bipartite operators J Biol Chem. 291:1235
  22. Chandran D, Scanlon MJ, Ohtsu K, Timmermans MC, Schnable PS, Wildermuth MC (2015)  Laser Microdissection-Mediated Isolation and In Vitro Transcriptional Amplification of Plant RNA. Curr Protoc Mol Biol. 112:25A.3.1
  23. Singhal R, Annarapu GK, Pandey A, Chawla S, Ojha A, Gupta A, Cruz MA, Seth T, Guchhait P. (2015)  Hemoglobin interaction with GP1ba induces platelet activation and apoptosis: a novel mechanism associated with intravascular hemolysis. Haematologica.100:1526
  24. Da Q, Teruya M, Guchhait P, Teruya J, Olson JS, Cruz MA (2015)  Free hemoglobin increases von Willebrand factor-mediated platelet adhesion in vitro: implications on circulatory devices. Blood.126:2338
  25. Kaur H, Salunke DM (2015)  Antibody promiscuity: Understanding the paradigm shift in antigen recognition. IUBMB Life 67:498.
  26. Verma S, Srikanth CV. (2015)  Understanding the complexities of Salmonella-host crosstalk as revealed by in vivo model organisms. IUBMB Life 67:482.
  27. Chandran D (2015)  Co-option of developmentally regulated plant SWEET transporters for pathogen nutrition and abiotic stress tolerance. IUBMB Life 67:461.
  28. Pandey A, Chawla S, Guchhait P (2015)  Type-2 diabetes: Current understanding and future perspectives. IUBMB Life 67:506.
  29. Kundu S, Kumar S, Bajaj A. (2015)  Cross-talk between bile acids and gastrointestinal tract for progression and development of cancer and its therapeutic implications. IUBMB Life 67:514.
  30. Bhattacharjee S, Noor JJ, Gohain B, Gulabani H, Dnyaneshwar IK, Singla A. (2015)  Post-translational modifications in regulation of pathogen surveillance and signaling in plants: The inside- (and perturbations from) outside story. IUBMB Life 67:524.
  31. Hanpude P, Bhattacharya S, Dey AK, Maiti TK (2015)  Deubiquitinating enzymes in cellular signaling and disease regulation. IUBMB Life 67:544.
  32. Nair DT, Kottur J, Sharma R (2015)  A rescue act: Translesion DNA synthesis past N2 -deoxyguanosine adducts. IUBMB Life 67:564.
  33. Krishnan V (2015)  Pilins in gram-positive bacteria: A structural perspective. IUBMB Life 67:533.
  34. Agarwal M, Kumar P, Mathew SJ (2015)  The Groucho/Transducin-like enhancer of split protein family in animal development. IUBMB Life 67:472.
  35. Kumar M, Pushpa K, Mylavarapu SV (2015)  Splitting the cell, building the organism: Mechanisms of cell division in metazoan embryos IUBMB Life 67:575.
  36. Jain D (2015)  Allosteric control of transcription in GntR family of transcription regulators: A structural overview. IUBMB Life 67:556.
  37. Verma S, Mohapatra G, Ahmed SM, Rana S, Jain S, Khalsa JK, Srikanth CV. (2015)  Salmonella engages host microRNAs to modulate SUMOylation: a new arsenal for intracellular survival. Mol Cell Biol.Jun 22. pii: MCB.00397-15. [Epub ahead of print] PubMed PMID: 26100020.
  38. Chaurasia P, von Ossowski I, Palva A, Krishnan V, (2015) Purification, crystallization and preliminary X-ray diffraction analysis of SpaD, a backbone-pilin subunit encoded by the fimbrial spaFED operon in Lactobacillus rhamnosus GG. Acta Crystallogr F71:103.
  39. S. Kumar, P. Bhargava, V. Sreekanth, and A. Bajaj, (2015) Design, Synthesis, and Physico-Chemical Interactions of Bile Acid Derived Dimeric Phospholipid Amphiphiles with Model Membranes. J. Colloid Interface Sci 448:398.
  40. K. Yadav, P. Bhargava, S. Bansal, M. Singh, S. Gupta, G. Sandhu, S. Kumar, V. Sreekanth, and A. Bajaj, (2015) Nature of the Charged Head Group Dictates the Anticancer Potential of Lithocholic Acid-Tamoxifen Conjugates For Breast Cancer Therapy, MedChemComm 6:778.
  41. A. Sharma, S. Bansal, A. A. Pohane, A. Bajaj, V. Jain, A. Srivastava. (2015) Cell-Penetrating Synthetic Antimicrobial Polypeptides (SAMPs) Exhibiting Potent and Selective Killing of Mycobacterium by Targeting its DNA. Chem Eur J 21:3540
  42. Kottur J, Sharma A, Gore KR, Narayanan N, Samanta B, Pradeepkumar PI, Nair DT. (2015) Unique Structural Features in DNA Polymerase IV Enable Efficient Bypass of the N(2) Adduct Induced by the Nitrofurazone Antibiotic. Structure 23:56.
  43. Weinert T, Olieric V, Waltersperger S, Panepucci E, Chen L, Zhang H, Zhou D, Rose J, Ebihara A, Kuramitsu S, Li D, Howe N, Schnapp G, Pautsch A, Bargsten K, Prota AE, Surana P, Kottur J, Nair DT, Basilico F, Cecatiello V, Pasqualato S, Boland A, Weichenrieder O, Wang BC, Steinmetz MO, Caffrey M, Wang M. (2015) Fast native-SAD phasing for routine macromolecular structure determination. Nat Methods 12:131.
  44. M Singh, S Bansal, S Kundu, P Bhargava, A Singh, R Motiani, R Shyam, V Sreekanth, S Sengupta, A Bajaj. (2015) Synthesis, Structure-Activity Relationship, and Mechanistic Investigation of Lithocholic Acid Amphiphiles for Colon Cancer Therapy. Med Chem Commun 6:192.
  45. Heesters BA, Das A, Chatterjee P, Carroll MC. (2014) Do follicular dendritic cells regulate lupus-specific B cells? Mol Immunol 62:283
  46. Singh K, Verma V, Yadav K, Sreekanth V, Kumar D, Bajaj A, Kumar V. (2014) Design, Regioselective Synthesis and Cytotoxic Evaluation of 2-Aminoimidazole-quinoline Hybrids Against Cancer and Primary Endothelial Cells. Eur J Med Chem 87:150.
  47. Bansal S, Singh M, Kidwai S, Bhargava P, Singh A, Sreekanth V, Kundu S, Singh R, Bajaj A. (2014) Bile Acid Amphiphiles with Tunable Head Groups as Highly Selective Non-hemolytic Antitubercular Agents. Med Chem Commun 5:1761.
  48. Singh M, Kundu S, Reddy A, Sreekanth V, Motiani RK, Sengupta S, Srivastava A, Bajaj A. (2014) Injectable Small Molecule Hydrogel for Localized and Sustained In Vivo Delivery of Doxorubicin. Nanoscale 6:12849.
  49. Khan T, Salunke DM. (2014) Adjustable locks and flexible keys: plasticity of epitope-paratope interactions in germline antibodies. J Immunol 192:5398.
  50. Gill J, Jayaswal P, Salunke DM. (2014) Antigen exposure leads to rigidification of germline antibody combining site. J Bioinform Comput Biol 12:1450006.
  51. Singh M, Bajaj A. (2014) Unraveling the Impact of Hydroxylation on Interactions of Bile Acid Cationic Lipids with Model Membranes by In-depth Calorimetry Studies. Phys Chem Chem Phys 16:19266.
  52. Bhargava P, Singh M, Sreekanth V, Bajaj A. (2014) Nature of the Charged Head Group Determines the Fusogenic Potential and Membrane Properties of Lithocholic Acid Phospholipids. J Phys Chem B 118:9341.
  53. Kim SH, Son GH, Bhattacharjee S, Kim, HJ, Nam JC, Nguyen PD, Hong JC, Gassmann W. (2014) The Arabidopsis immune adaptor SRFR1 interacts with TCP transcription factors that redundantly contribute to effector-triggered immunity. Plant J 78:978.
  54. Lorenzo LR, Huff C, Myllymäki M, Olenchock B, Swierczek S, Tashi T, Gordeuk V, Wuran T, Li GR, McClain DL, Khan TM, Koul PA, Guchhait P, Salama ME, Xing J, Semenz GL, Liberzon E, Wilson A, Simonson TS, Jorde LB, Kaelin Jr WG, Koivunen P, Prchal JT. (2014) A genetic mechanism for Tibetan high-altitude adaptation. Nature Genetics 46:951.
  55. Salunke DM, Gill J, Dwevedi A. (2014). Comparative structural proteomics of allergenic proteins from plant pollen. J Ind Inst Sci 94:119.
  56. Vedagopuram S, Bajaj A. (2013) Number of Free Hydroxyl Groups on Bile Acid Phospholipids Determines the Fluidity and Hydration of Model Membranes. J Phys Chem B 117:12135.
  57. Sharma S, Kundu S, Reddy AM, Bajaj A, Srivastava A. (2013) Design and Engineering of Stable and Biocompatible Disulfide-cross-linked Nanocomplexes of Polyamide Polyelectrolytes for Cytosolic Delivery of Entrapped Peptide Cargo. Macromol Biosci 13:927.
  58. Vedagapuram S, Bansal S, Motiani R, Kundu S, Muppu SK, Datta T, Panjamurthy K, Sengupta S, Bajaj A. (2013) Design, Synthesis, and Mechanistic Investigations of Bile Acid-Tamoxifen Conjugates for Breast Cancer Therapy. Bioconjugate Chem 24:1468.
  59. Singh M, Singh A, Kundu S, Bansal S, Bajaj A. (2013) Interactions of Bile Acid based Facial Amphiphiles with Membranes Influences their Anticancer Activities for Colon Cancer. Biophys Biochim Acta Biomembr 1828:1926.
  60. Vedagopuram S, Bajaj A. (2013) Fluorescece (Fluidity/Hydration) and Calorimetric Studies of Interactions of Bile Acid Tamoxifen Conjugates with Model Membranes. J Phys Chem B117:2123.
  61. Deepak S, Ingemar von O, Airi P, Vengadesan K, (2013) Purification, Crystallization and Preliminary Crystallographic Analysis of the SpaA Backbone-pilin Subunit from Probiotic Lactobacillus rhamnosus GG. Acta Crystallogr F69:1182.
  62. Vengadesan K, Macon K, Sugumoto S, Mizunoe Y, Iwase T, Narayana SVL. (2013) Purification, Crystallization and Preliminary X-ray Diffraction Analysis of the Staphylococcus epidermidis Extracellular Serine Protease Esp. Acta Crystallogr F 69:49.
  63. Krishnan V, Dwivedi P, Kim BJ, Samal A, Macon K, Ma X, Mishra A, Doran KS, Ton-That H, Narayana SV. (2013) Crystal Structure of Streptococcus agalactiae tip pilin GBS104; A Model GBS Pili Assembly and Host Interactions. Acta Crystallogr D 69:1073.
  64. Chen C, Krishnan V, Macon K, Manne K, Narayana SV, Schneewind O. (2013) Secreted Proteases Control Autolysin-mediated Biofilm Growth of Staphylococcus aureus. J Biol Chem 288:29440.
  65. Sharma R, Lomash S, Salunke DM. (2013) Putative bioactive motif of tritrpticin revealed by an antibody with biological receptor-like properties. PLoS One 8:e75582
  66. Bhattacharjee S, Garner CM, Gassmann W. (2013) New clues in the nucleus: Transcriptional reprogramming in effector-triggered immunity. Front Plant Sci 4:364.
  67. Tapryal S, Gaur V, Kaur KJ, Salunke DM. (2013) Structural evaluation of a mimicry recognizing paratope: plasticity in antigen–antibody interactions manifests in molecular mimicry. J Immunol 191:456.
  68. Rajiv L Tiwari, Gowtham K Annarapu, Prasenjit Guchhait. (2013) Pathophysiological consequences of hemolysis in sickle cell disease in "Sickle Cell Disease" (Ed. D Acuna-Costroviejo and I Rusanova) Nova Science Publishers, pp. 69.
  69. Bhowmick A and Salunke DM. (2012) Limited conformational flexibility in the paratope may be responsible for degenerate specificity of HIV epitope recognition. Int Immunol 25:77.
  70. Khan T and Salunke DM. (2012) Structural Elucidation of the Mechanistic Basis of Degeneracy in the Primary Humoral Response. J Immunol 188:1819.
  71. Tomar D, Khan T, Singh RR, Mishra S, Gupta S, Surolia A, Salunke DM. (2012) Crystallographic study of novel transthyretin ligands exhibiting negative-cooperativity between two thyroxine binding sites. Plos One 7:e43522.
  72. Rana S, Singla AK, Bajaj A, Elci SG, Miranda OR, Mout R, Yan B, Jirik FR, Rotello VM. (2012) Array-Based Sensing of Metastatic Cells and Tissues Using Nanoparticle-Fluorescent Protein Conjugates. ACS Nano 6:8233.
  73. Salunke DM, Kaur H, Gill J. (2012) New paradigms in antibody specificity: Structural biology of antigen recognition by germline antibodies in ‘Biomolecular forms and functions’ (Ed. M. Bansal and N. Srinivasan) World Scientific Publishing, pp. 173.
  74. Biswas J, Bajaj A, Bhattacharya S. (2011) Membranes of Cationic Gemini Lipids based on Cholesterol with Hydroxyl Headgroups and their Interactions with DNA and Phospholipid. J Phys Chem B 115:478.
  75. Gaur V, Chanana V, Jain A, Salunke DM. (2011) The structure of a haemopexin-fold protein from cow pea (Vigna unguiculata) suggests functional diversity of haemopexins in plants. Acta Crystallogr F 67:193.
  76. Rana S, Bajaj A, Mout R, Rotello VM. (2011) Monolayer Coated Gold Nanoparticles for Delivery Applications. Adv Drug Del Rev 64:200.
  77. Saha K, Bajaj A, Duncan B, Rotello VM. (2011) Beauty is Skin Deep: A Surface Monolayer Perspective on Nanoparticle Interactions with Cells and Biomacromolecules. Small 7:1903.
  78. Tapryal S, Krishnan L, Batra JK, Kaur KJ, Salunke DM. (2010) Cloning, expression and efficient refolding of carbohydrate-peptide mimicry recognizing single chain antibody 2D10. Protein Express Purif 72:162.
  79. Lomash S, Nagpal S, Salunke DM. (2010) An antibody as surrogate receptor reveals determinants of activity of an innate immune peptide antibiotic. J Biol Chem 285: 35750.

 

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