Regional Centre for Biotechnology

2019

Pratap S, Megta A.K, Krishnan V. (2019) Sortases from a Probiotic Lactobacillus rhamnosus GG: Cloning, Expression, Purification, Crystallization and Preliminary X-Ray Diffraction Study. Crystallography Reports. 64-1117
Bhasym A, Bhakuni T, Guchhait P. (2019) Elevated surface-bound complement FH alters the function of platelets and monocytes in FHR1/3 null healthy individuals. Blood Cells Mol Dis. 79:102349
Joshi H, Malik A, Aggarwal S, Munde M, Maitra SS, Adlakha N, Bhatnagar R. (2019) In-vitro Detection of Phytopathogenic Fungal Cell Wall by Polyclonal Sera Raised Against Trimethyl Chitosan Nanoparticles. nt J Nanomedicine. 14-10023
Kumar Tripathi S, Salunke DM (2019) Exploring the Different States of Wild-type T-cell receptor and Mutant Conformational Changes towards Understanding the Antigen Recognition. J Biomol Struct Dyn. 24:1
Sharma S.C, Kumar A, Vashisht S & Salunke D.M. (2019) High resolution structural and functional analysis of a hemopexin motif protein from Dolichos Scientific Reports. 19828
Li H, Rai M, Buddika K, Sterrett MC, Luhur A, Mahmoudzadeh NH, Julick CR, Pletcher RC, Chawla G, Gosney CJ, Burton AK, Karty JA, Montooth KL, Sokol NS, Tennessen JM. (2019) Lactate dehydrogenase and glycerol-3-phosphate dehydrogenase cooperatively regulate growth and carbohydrate metabolism during Drosophila melanogaster larval development. Development 146:17
Pandey M, Bansal S, Chawla G. (2019) Molecular Approaches for Analysis of Drosophila MicroRNAs Springer Protocols Handbooks 169:188
Chawla G. (2019) Healthy Aging Research in India Medwin Publishers 2:1
Thakur S.K. , Goswami K, Bhattacharjee S, Soni U, Guchhait P, Eswaran SV. (2019) A Water Soluble Single Walled Carbon Nanotube Aryl Aziridino Carboxylic Acid Decorated Mn (II) Complex Increased Root Growth in Arabidopsis thaliana. Chemistry Select. doi.org/10.1002/slct.201904205
Gupta M, Sharma G, Saxena D, Budhwar R, Vasudevan M, Gupta V, Gupta A, Gupta R, Chandran D. (2019) Dual RNA-Seq analysis of Medicago truncatula and the pea powdery mildew Erysiphe pisi uncovers distinct host transcriptional signatures during incompatible and compatible interactions and pathogen effector candidates. Genomics | 30612-3
Suhail A, Rizvi ZA, Mujagond P, Ali SA, Gaur P, Singh M, Ahuja V, Awasthi A, Srikanth CV. (2019) DeSUMOylase SENP7-Mediated Epithelial Signaling Triggers Intestinal Inflammation via Expansion of Gamma-Delta T Cells. Cell Rep. 3522-3538
Madni ZK, Tripathi SK, Salunke DM. (2019) Structural insights into the lipid transfer mechanism of a non-specific lipid transfer protein. Plant J. Doi: 10.1111/tpj.14627. [Epub ahead of print]
Kumar Megta A, Palva A, von Ossowski I, Krishnan V. (2019) SpaB, an atypically adhesive basal pilin from the lactobacillar SpaCBA pilus: crystallization and X-ray diffraction analysis. Acta Crystallogr F Struct Biol Commun. F75:731
Banerjee A, Tripathi A. (2019) Recent advances in understanding Japanese encephalitis. F1000Res. DOI: 10.12688/f1000research.19693.1
Thalla M, Kant K, Sharma D, Rawat R, Banerjee S. (2019) Merged experimental guided computational strategy toward tuberculosis treatment mediated by alveolar macrophages mannose receptor. J Biomol Struct Dyn. DOI: 10.1080/07391102.2019.1697369
Shikhi M, Jain A, Salunke DM. (2019) Comparative study of 7S globulin from Corylus avellana and Solanum lycopersicum revealed importance of salicylic acid and Cu-binding loop in modulating their function. Biochem Biophys Res Commun | doi: 10.1016/j.bbrc.2019.11.072. [Epub ahead of print]
Sharma KB, Sharma M, Aggarwal S, Yadav AK, Bhatnagar S, Vrati S, Kalia M. (2019) Quantitative Proteome Analysis of Atg5-Deficient Mouse Embryonic Fibroblasts Reveals the Range of the Autophagy-Modulated Basal Cellular Proteome. mSystems. | 4(6). pii: e00481-19.
Kumar R, Kumar S, Hanpude P, Singh AK, Johari T, Majumder S & Maiti TK (2019) Partially oxidized DJ-1 inhibits α-synuclein nucleation and remodels mature α-synuclein fibrils in vitro. Communications Biology | 2:395
Banerji A, Suri F (2019) Impact of R and D Intensity, Patents and Regulatory Filings on Export Intensity of Indian Pharmaceutical Industry Indian Journal of Pharmaceutical Education and Research | 53(4):638-648
Narayanan N, Banerjee A, Jain D, Kulkarni D.S., Sharma R, Nirwal S, Rao D.N, Nair D.T (2019) Tetramerization at low pH licenses DNA methylation activity of M.HpyAXI in the presence of acid stress. Journal of Molecular Biology | Doi.org/10.1016/j.jmb.2019.10.001
Yadav AK, Sahoo PK, Goswami HN, Jain D (2019) Transcriptional fidelity of mitochondrial RNA polymerase RpoTm from Arabidopsis thaliana. J Mol Biol | Doi: 10.1016/j.jmb.2019.08.022
Gabriela Krejčová, Adéla Danielová, Pavla Nedbalová, Michalina Kazek, Lukáš Strych, Geetanjali Chawla, Jason M. Tennessen, Jaroslava Lieskovská, Marek Jindra, Tomáš Doležal, and Adam Bajgar (2019) Drosophila macrophages switch to aerobic glycolysis to mount effective antibacterial defense. eLife 2019;8:e50414 | DOI: 10.7554/eLife.50414
Sharma G, Aminedi R, Saxena D, Gupta A, Banerjee P, Jain D, Chandran D (2019) Effector mining from the Erysiphe pisi haustorial transcriptome identifies novel candidates involved in pea powdery mildew pathogenesis. Mol. Plant Pathol. | doi.org/10.1111/mpp.12862
Pal S, Medatwal N, Kumar S, Kar A, Komalla V, Yavvari P.S., Mishra D, Rizvi Z.R., Nandan S, Malakar D, Pillai M, Awasthi A, Das P, Sharma R. D., Srivastava A, Sengupta S, Dasgupta U, and Bajaj A (2019) A Localized Chimeric Hydrogel Therapy Combats Tumor Progression through Alteration of Sphingolipid Metabolism ACS Central Sci | doi.org/10.1021/acscentsci.9b00551
S Ankur, DS Atul, M Jignesh, S Nishith, K Meena , CK Avinash ,RC Subhasree , G Prasenjit , K Surajit (2019) Disulfide-Bridged Chitosan-Eudragit S-100 Nanoparticles for Colorectal Cancer ACS Appl. Nano Mater | 6409-6417
Johnson MK, Kottur J, Nair DT. (2019) A polar filter in DNA polymerases preventsribonucleotide incorporation. Nucleic Acids Res. 10693-10705
Ghodke PP, Bommisetti P, Nair DT, Pradeepkumar PI. (2019) Synthesis of N(2)-Deoxyguanosine Modified DNAs and the Studies on Their Translesion Synthesis by the E. coli DNA Polymerase IV. J Org Chem| 84:1734
Grover R, Burse SA, Shankrit S, Aggarwal A, Kirti K, Narta K, Srivastav R, Ray AK, Malik G, Vats A, Motiani RK, Thukral L, Roy SS, Bhattacharya S, Sharma R, Natarajan K, Mukerji M, Pandey R, Gokhale RS and Natarajan VT (2019). Myg1 exonuclease couples the nuclear and mitochondrial translational programs through RNA processing. Nucleic Acid Research. 5852-5866.
Selokar NL, Sharma P, Saini M, Sheoran S, Rajendran R, Kumar D, Sharma RK, Motiani RK, Kumar P, Jerome A, Khanna S, Yadav PS (2019). Success cloning of a superior breeding bull. Sci Rep. 2019 Aug 6;9(1):11366.
Gupta S, Thakur J, Pal S, Gupta R, Mishra D, Kumar S, Yadav K, Saini A, Yavvari P, Vedantham M, Singh A, Srivastava A, Prasad R and Bajaj A (2019) Cholic Acid-Peptide Conjugates (CAPs) as Potent Antimicrobials against Interkingdom Polymicrobial Biofilms. Antimicrobial Agents Chemotherapy | 63:11
Vashisht S, Verma S, Salunke DM. (2019) Cross-clade antibody reactivity may attenuate the ability of influenza virus to evade the immune response. Mol Immunol | 114:149
Bhasym A, Bhakuni T and Guchhait P. (2019) Elevated surface-bound complement factor-H alters the function of platelets and monocytes in FHR1/3-null healthy individuals. Blood Cells Molecules Diseases | Doi.org/10.1016/j.bcmd.2019.102349
Kumar S, Thakur J, Yadav K, Mitra M, Pal S, Ray A, Gupta S, Medatwal N, Gupta R, Mishra D, Rani P, Padhi S, Sharma P, Kapil Ar, Srivastava A, Priyakumar, U Deva, Dassgupta U, Thukral L, Bajaj A. (2019) Cholic Acid-Derived Amphiphile can Combat Gram-Positive Bacteria-mediated Infections via Disintegration of Lipid Clusters. ACS Biomaterials Sci & Eng. | Doi.org/10.1021/acsbiomaterials.9b00706
Kidwai S, Bouzeyne R, Chakraborti S, Khare N, Das S, Gosain T, Behura A, Meena C, Dhiman R, Essafi M, Bajaj A, Saini D, Srinivasan N, Mahajan D and Singh R. (2019) NU-6027 inhibits growth of Mycobacterium tuberculosis by targeting Protein Kinase D and Protein Kinase G. Antimicrobial Agents Chem | DOI: 10.1128/AAC.00996-19
Sreekanth V and Bajaj A (2019) Recent Advances in Engineering of Lipid-Drug Conjugates for Cancer Therapy.ACS Biomaterials Sci. & Eng | Doi.org/10.1021/acsbiomaterials.9b00689
P Banerjee, Chanchal, D Jain (2019) Sensor I regulated ATPase activity of FleQ is essential for motility to biofilm transition in Pseudomonas aeruginosa ACS Chemical Biology | doi.org/10.1021/acschembio.9b00255
Kumar H, Pushpa K, Kumari A, Verma K, Pergu R, Mylavarapu SVS. (2019) The Exocyst complex and Rab5 are required for abscission by localizing ESCRT III subunits to the cytokinetic bridge. J Cell Sci | Doi: 10.1242/jcs.226001. [Epub ahead of print]
Verma J, Bag S, Saha B, Kumar P, Ghosh TS, Dayal M, Senapati T, Mehra S, Dey P, Desigamani A, Kumar D, Rana P, Kumar B, Maiti TK, Sharma NC, Bhadra RK, Mutreja A, Nair GB, Ramamurthy T, Das B. (2019) Genomic plasticity associated with antimicrobial resistance in Vibrio cholerae. Proc Natl Acad Sci U S A. | 116:6226
Mukherjee S, Akbar I, Kumari B, Vrati S, Basu A and Banerjee A (2019) Japanese Encephalitis Virus-induced let-7a/b interacted with the NOTCH-TLR7 pathway in microglia and facilitated neuronal death via caspase activation. J Neurochem | 149:518
Puraswani M, Khandelwal P, Saini H, Saini S, Gurjar B.S., Sinha A, Shende R.P, Maiti T.K, Singh A.K, Kanga U, Ali U, Agarwal I, Anand K, Prasad N, Rajendran P, Sinha R, Vasudevan A, Saxena A, Agarwal S.K., Hari P, Sahu A, Rath S and Bagga A (2019) Clinical and immunological profile of anti-factor H antibody associated atypical hemolytic uremic syndrome: A nationwide database Front. Immunol. | 10:1282
Bhasym A, Annarapu GK, Saha S, Shrimali N, Gupta S, Seth T, Guchhait P. (2019) Neutrophils develop rapid proinflammatory response after engulfing Hb-activated platelets under intravascular hemolysis. Clin Exp Immunol | Doi: 10.1111/cei.13310
Sharma Y, Ahmad A, Yavvari PS, Kumar S, Bajaj A, Khan F (2019) Targeted SHP-1 silencing modulates macrophage phenotype leading to metabolic improvement in dietary obese mice. Molecular Therapy Nucleic Acids | 16:626
Megta AK, Mishra AK, Palva A, von Ossowski I, Krishnan V (2019) Crystal structure of basal pilin SpaE reveals the molecular basis of its incorporation in the lactobacillar SpaFED pilus. J Struct Biol | 207:74
R Mehra, S Bhushan, F Bast, S Singh (2019) Marine macroalga Caulerpa: role of its metabolites in modulating cancer signaling. Molecular Biology Reports | 46:3545
Bhakuni T, Singhal R, Aannarapu GK, Sharma A, Mahapatra M, Saxena R, Guchhait P (2019) Unique case of autoantibody mediated inactivation of ADAMTS13 in an Indian TTP patient. Blood Cells Molecules Diseases | 77:29
Bhasym A, Gurjar BS, Sriharsha TM, Bhasym A, Prabhu S, Puraswani M, Khandelwal P, Saini H, Saini S, Verma AK, Chatterjee P, Bal V, George A, Sharma A, Hari P, Sinha A, Bagga A, Rath S, Guchhait P (2019) Altered Peripheral Blood Leucocyte Phenotype and Responses in Healthy Individuals with Homozygous Deletion of FHR1 and FHR3 Gene. J Clinical Immunology | 39:336
R Singhal, DK Rathore, T Bhakuni, T Seth, P Guchhait (2019) Absence of Nonclassical Monocytes in Hemolytic Patients : Free Hb and NO-Mediated Mechanism Journal of Immunology Research | 2019:1
Pergu R, Dagar S, Kumar H, Kumar R, Bhattacharya J, Mylavarapu SVS (2019) The chaperone ERp29 is required for tunneling nanotube formation by stabilizing MSec. J Biol Chem | 294:7177
Vemanna RS, Bakade R, Bharti P, Kumar MKP, Sreeman SM, Senthil-Kumar M and Makarla U (2019) Cross-Talk Signaling in Rice During Combined Drought and Bacterial Blight Stress Front. Plant Sci | 10:193
Das S, Kumar P, Verma A, Maiti TK, Mathew SJ. (2019) Myosin heavy chain mutations that cause Freeman-Sheldon syndrome lead to muscle structural and functional defects in Drosophila. | Developmental Biology | 449:90
Awasthi A, Kumar P, Srikanth CV, Sahi S, Puria R. (2019) Invitro Evaluation of Torin2 and 2, 6-Dihydroxyacetophenone in Colorectal Cancer Therapy. Pathol Oncol Res | 25:301
SK Thakur, M Srivastava, A Kumar, R Goel, S Asthana, Eswaran S.V (2019) A Multidimensional Approach to Explore the Use of a Small Heterobifunctional Crosslinker based on a Metabolite of the Kynurenine Pathway. J Proteomics Bioinform | 12:10
Kandanur SGS, Kundu S, Cadena C., Juan HS, Bajaj A, Guzman JD, Nanduri S, Golakoti NR, (2019) Design, synthesis, and biological evaluation of new 12‐substituted‐14‐deoxy‐andrographolide derivatives as apoptosis inducers. Chemistry Lett | 73:1669
Yavvari PS, Verma P, Mustfa SA, Pal S, Kumar S, Awasthi AK, Ahuja V, Srikanth CV, Srivastava A, Bajaj A. (2019) A nanogel based oral gene delivery system targeting SUMOylation machinery to combat gut inflammation. Nanoscale | 11:4970
Bhatnagar S, Majumder P.P, Salunke D.M (2019) A Pregnancy Cohort to Study Multidimensional Correlates of Preterm Birth in India: Study Design, Implementation, and Baseline Characteristics of the Participants. American Journal of Epidemiology | 188:621
Srivastava A, Yavvari PS, Awasthi AK, Sharma A, Bajaj A. (2019) Emerging Biomedical Applications of Polyaspartic Acid-Derived Biodegradable Polyelectrolytes and Polyelectrolyte Complexes. J. Mater. Chem. | 7:2102
Madhvi A, Hingane S, Srivastav R, Joshi N, Subramani C, Muthumohan R, Khasa R, Varshney S, Kalia M, Vrati S, Surjit M, Ranjith-Kumar CT (2017)A screen for novel hepatitis C virus RdRp inhibitor identifies a broad-spectrum antiviral compound. Sci Rep | 7:5186
Jain D, Salunke DM (2019) Antibody specificity and promiscuity. Biochem J | 476:433
K Kumar, F Askari, MS Sahu, R Kaur (2019) Candida glabrata: A Lot More Than Meets the Eye.Microorganisms | 7:39
Mitra M, Asad M, Kumar S, Yadav K, Chaudhary S, Bhavesh N.S., Khalid S, Thukral L and Bajaj A (2019) Distinct Intramolecular Hydrogen Bonding Dictates Antimicrobial Action of Membrane-Targeting Amphiphiles. J. Phys. Chem. Lett | 10:754
Yadav K, Kumar S, Mishra S, Asad M, Mitra M, Yavvari PS, Gupta S, Vedantham M, Ranga P, Komalla V, Pal S, Sharma P, Kapil A, Singh A, Singh N, Srivastava A, Thukral L and Bajaj A (2019)Deciphering the Role of Intramolecular Networking in Cholic Acid-Peptide Conjugates (CAPs) at Lipopolysaccharide Surface in Combating Gram-negative Bacterial Infections. J. Med. Chem. | 62:1875
Dwivedi D, Kumari A, Rathi S, Mylavarapu SVS, Sharma M. (2019) The dynein adaptor Hook2 plays essential roles in mitotic progression and cytokinesis.J Cell Biol | 218:871
Yadav K, Yavvari PS, Pal S, Kumar S, Mishra D, Gupta S, Mitra S, Soni V, Khare N, Sharma P, Srikanth C.V, Kapil A, Singh A, Nandicoori V.K, Bajaj A. (2019) Oral Delivery of Cholic Acid-Derived Amphiphile Helps in Combating Salmonella-mediated Gut Infection and Inflammation Bioconjugate Chem. | 30:721
Mylavarapu S, Kumar H, Kumari S, Sravanthi LS, Jain M, Basu A, Biswas M, Mylavarapu SVS, Das A, Roy M. (2019) Activation of Epithelial-Mesenchymal Transition and Altered β-Catenin Signaling in a Novel Indian Colorectal Carcinoma Cell Line. Front. Oncol. | 9:54
Ghodke PP, Bommisetti P, Nair DT, Pradeepkumar PI. (2019) Synthesis of N2 -deoxyguanosine modified DNAs and the studies on their translesion synthesis by the E. coli DNA polymerase IV. J Org Chem. | 84:1734
Kumariya R, Garsa AK, Rajput YS, Sood SK, Akhtar N, Patel S. (2019) Bacteriocins: Classification, synthesis, mechanism of action and resistance development in food spoilage causing bacteria. Microb Pathog. 128:171