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Dr. S. V. Eswaran

Visiting Scientist
E-mail: samba.eswaran at rcb dot res dot in

  • Ph.D., 1973, University of Delhi, India.

(i) The discovery of the new molecule "Viswamayene" (named after the late Prof M A Viswamitra, IISC, Bangalore and a famous X-ray crystallographer). The formation of these unusual molecules involves 'long-lived' transients and nitrene-carbene conversion. Subsequently, the life span of one such transient was measured by ultra-fast spectroscopy to be 700 picoseconds

(ii) Homo and hetero-bifunctional crosslinkers based on 'long lived' transients are known to yield to more efficient intermolecular crosslinking of peptides/proteins. Thus crosslinking of lysozyme has been successfully carried out by us. The new technique of chemical crosslinking-mass spectrometry-bioinformatics is very useful for such studies. The distance constraints between the interacting amino acids in proteins can thus be determined. This is expected to play a major tool in proteomics, systems/ structural biology and the origin of diseases. Crosslinking of a-Crystallin, the transparent protein of the human eye lens is being studied. This in turn leads to Cataractogenesis, i.e. the origin of Cataract. We are especially looking for collaborative work on studies on protein complexes.

(iii) Such 'Long Lived' transients covalently bind to Nanocarbon materials (fullerene C60, SWCNT/ MWCNT, Graphene) very efficiently making them easily soluble in common organic solvents. This paves the way for using such adducts for preparing Solar Cells and for use in Organic Electronics. Cytoxicity studies on the above adducts is also being carried out to employ these for nano-drug delivery.

  • Sujeet Kumar Thakur
    Scientific Assistant
    sujeet@rcb.res.in
    • Dr A.P.J Abdul Kalam life time Achievement Award 2016, The Society of Biomedical Laboratory Scientists, India
    • INSA teacher award, 2013
    • Nominated by Sri Venkateswara College, University of Delhi for a lifetime dedicated to undergraduate teaching as “Teacher of Eminence”, 2013
    • CRSI Best teacher award, 2007
    • University of Delhi distinguished teacher award, 2009;
    • DADD-UGC fellow, 1976-77.
    • Atomic Energy Commission Post-graduate Scholarship, 1967-68
    • Listed in IBC Outstanding Scientists Worldwide 2007
    • Nominated as International Scientist of the Year 2007
    • Included in Marquis Who’s Who in the World 2010;
    • Included in 1999 Edn., of International Directory of Awarded the Distinguished Leadership, published by the American Biographical Institute.
    • Member, Expert Committee, DBT Star Colleges Committee, 2011-2014.
    • Appointed as a Local Commissioner by the High Court of Haryana and Punjab and Court in New Jersey in a patent case, 2011-
    • Member, Board of Research Studies, Faculty of Science, University of Delhi, and Department Research Committee, Chemistry Department, University of Delhi 2008-10.
    • Invited by the Lindau Committee to attend the Nobel Laureates meeting at Lindau, Germany, 2009.
    • Served as Mentor, Indian team to Chemistry Olympiad, Moscow, 2007
    • Member, Academic Council, Delhi University, 2001-2003.
    • Served as a member of the Planning & Program Committee of the National Science Centre, Delhi.
    • Served as member of the Faculty of Science & the Board of Research Studies, University of Delhi, Delhi.
    • Served as editor of Resonance, a science magazine published by the Indian Academy of Science, Bangalore.
    • Was a member of the Indian delegation to the International Conference on Chemical Education held at the University of Maryland, 1981.
    • Have served as Ph.D. examiner of some Indian Universities.
    • Served as a referee for research papers in many reputed journals.
    • Invited to teach courses for M. Sc. Agrochemicals & Pest Management Course at the University of Delhi since Feb. 1992.
    • Organized student chemical demonstrations including chemi-luminescence, oscillating chemical reactions, liquid crystals, etc. at the Indian Science Congress, Delhi, Jan. 1997.
    • Served as expert for KVPY scholarship interviews.
    • Served as expert monitoring Committee, Ministry of Information and Technology, Govt. of India for a strategic research project at NCL, Pune and IICT, Hyderabad
    • Eswaran SV, Kaurb D, Khamarue K, Prabhakarc S, Sonyc T , Raghunathand P, Gangulye B, (2016) Tuning the strain effect to induce selectivity through intramolecular nitrene insertion into an adjacent methoxy Csingle bondH bond leading to form a new benzoxazole: experimental and computational studies.Tetrahedron Letters. 57:1899
    • Hole Mobilty Studies on Dehydrodivanillin based New Blue-green Emitting Poly (p-phenylenevinylenes), Manoj Gaur, Jaya Lohani, V. R.Balakrishnan, P. Raghunathan and S. V. Eswaran, Chem Sci Rev and Lett, (2014), 3 (11), 436-443.
    • Concomitant Nitrene and Carbene Insertion Accompanying Ring Expansion: Spectroscopic, X-ray and Computational Studies J Divneet Kaur, Hoi L. Luk, William Coldren, Pavan M. Srinivas, Lakshetti Sridhar, Sripadi Prabhakar, Partha Raghunathan, T. N. Guru Row, Christopher M. Hadad, Matthew S. Platz and Sambasivan V. Eswaran J. Org. Chem. (2014) 79, 1199-1205
    • Grasshoppers-Generalists to Specialists?, S. V. Eswaran and Akansha Jindal, Resonance, (2013), 18, 810-816
    • J. Xue, H. L. Luk, S. V. Eswaran, and M.S. Platz, (2012), Ultrafast Infrared and UV-vis Studies of the Photochemistry of 2-Methoxy-6-Methoxycarbonylphenyl Azide in Solution; J. Phys. Chem. A, 116, (22), 5325-53346
    • Maneesh Sharma, A.A. Naik, P. Raghunathan and S.V. Eswaran, Evaluation of Microlithographic Performance of “Deep UV” Resists:Synthesis & 2D NMR Studies on Alternating “High Ortho” Novolak Resins; (2012) J. Chemical Science, 124, 395–401
    • Manoj Gaur, Mayurika Goel, L. Sridhar, Tara Devi S. Ashok, S. Prabhakar, P. Dureja, P. Raghunathan and S. V. Eswaran (2012), Synthesis, characterization and antifungal activity of biaryl based bis-1, 2, 3- triazoles using Click reaction, Monatshefte fuer Chemie, 143:283-288
    • Jaya Lohani, V. R. Balakrishnan, Manoj Gaur, P. Raghunathan, S. V. Eswaran, (2011), Biaryl Crosslinkers I. Crosslinking of a Bis-azidobiaryl with Poly (3-hexylthiophene), Canadian J. Chem., 89:(5) 549-554
    • M Sharma, R Bhatia, V Gupta, S Chand, P Raghunathan and S. V. Eswaran, Soluble Functionalised Fullerenes for Photovoltaics Synthetic Metals. 161, (2011). 844-84
    • Manoj Gaur, Jaya Lohani, R. Raman, V.R. Balakrishnan P. Raghunathan and S.V. Eswaran (2010) Improved device performance based on crosslinking of poly (3-hexylthiophene), Synthetic Metals 160, 2061–2064
    • Jaya Lohani, Manoj Gaur, Upendra Kumar, V. R. Balakrishnan, Harsh, S. V. Eswaran (2010) Electrical Studies on Pentacene Thin Film Transistors with Different Channel Widths, Chin. Phys. Lett. Vol. 27, No. 4 048102
    • Gaur, M., Lohani, J., Balakrishnan, V. R., Raghunathan, P. and Eswaran, S. V. (2009) Dehydrodivanillin: Multidimensional NMR Spectral Studies, Surface Morphology and Electrical Characteristics of Thin Films. Bull Korean Chem. Soc. 30 (12), 2895-2898.
    • Eswaran, S. V. (2009) Why does the grasshopper not eat spinach? Resonance (2009), 14, 978-982.
    • Sharma, M., Naik, A. A., Gaur, M., Raghunathan, P. and Eswaran, S. V. (2009) Azido-m-meconine-‘high ortho’: Novolak resin based negative photoresists for deep UV lithography J. Chem. Sci., 121, 503-508.
    • Sharma, M., Hopson, R., Raghunathan, P. and Eswaran, S. V. (2009) m/ p-Cresol–Based t-BOC Protected Alternating ‘‘High Ortho’’ Copolymer as a Possible e-Beam Resist: Characterization Using Multidimensional NMR Spectroscopy J. Appl. Polym. Sci. 113, 2166–2172.

Patents

    • Eswaran, S. V., Basu, P. K. and Roy, D., "High Ortho: Novolac Copolymers and Composition Thereof: Indian patent (2010) IN 238971
    • Eswaran, S. V. A process for the preparation of a negative photoresist composition. Indian Patent (2002). IN 187078
    • Eswaran, S. V. Process for preparation of negative photoresist. Indian Patent (2002), IN 187523
    • Eswaran, S. V. Preparation of crystalline 5, 6-dimethoxybenzofuroxan Indian Patent (1993), IN 172050
    • Eswaran, S. V. Negative photoresist and a process thereof. Canadian Patent (1995), CA 2106231
    • Eswaran, S. V. Photoresist composition and method of its production. French Patent, (1995) FR 2710762
    • Eswaran, S. V. Process for preparation of a Dimethoxy indoloquinoxaline dioxide useful as a bacteriostatic and feed additive. Indian 1992, IN 170838

Dr. S. V. Eswaran
Emeritus Scientist-CSIR & Emeritus Professor-AcSIR
Regional Centre for Biotechnology
NCR Biotech Science Cluster
3rd Milestone, Faridabad-Gurgaon Expressway
P.O. Box No. 3, Faridabad - 121 001
Haryana (NCR Delhi), India
Phone: 0129 - 2848801
E-mail: samba.eswaran at rcb dot res dot in
Phone: 91 129-2848888

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